Recombinant human BMP2 protein (Active) (ab50099)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, Cellular Activation, SDS-PAGE
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Product name
Recombinant human BMP2 protein (Active)
See all BMP2 proteins and peptides -
Biological activity
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
The expected ED50 for this effect is 0.5-1.0 μg/ml.
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Purity
> 98 % SDS-PAGE.
>98% by HPLC analyses. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR -
Predicted molecular weight
26 kDa -
Amino acids
283 to 396 -
Additional sequence information
Homodimeric protein consisting of two 115 amino acid polypeptide chains. Full length mature protein, minus the signal peptide and the propeptide.
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Preparation and Storage
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Alternative names
- BDA2
- BMP-2
- BMP-2A
see all -
Function
Induces cartilage and bone formation. -
Tissue specificity
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
