Anti-TGF beta 1 antibody [TB21] (ab27969)
Key features and details
- Mouse monoclonal [TB21] to TGF beta 1
- Reacts with: Sheep, Human
- Isotype: IgG1
Overview
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Product name
Anti-TGF beta 1 antibody [TB21]
See all TGF beta 1 primary antibodies -
Description
Mouse monoclonal [TB21] to TGF beta 1 -
Host species
Mouse -
Specificity
This antibody recognises natural and recombinant TGF beta 1. It reacts with both dimeric and monomeric natural forms under reducing and non reducing conditions. Full length, inactive 44 kD TGFB1 is cleaved into mature TGFB1 (13 kD). TGFB1 also homodimerizes and heterodimerizes with TGFB2, so there is potential for multiple different band sizes in WB. -
Species reactivity
Reacts with: Sheep, Human
Predicted to work with: Rat
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Immunogen
Human TGF Beta 1 from human platelets.
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Positive control
- Purchase matching WB positive control:Recombinant human TGF beta 1 protein (Active)
- Human breast carcinoma.
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General notes
We have mixed feedback from customers about the Rat specificity so the Rat species has been moved to predicted as we can't guarantee it. The antibody has been successfully used with Rat samples in publication PMID 22471627 and PMID 19820199 though.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservative: 0.09% Sodium azide -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
This clone (TB21) demonstrates neutralising activity against TGF beta 1 in cell proliferation assays. Removal of sodium azide is recommended prior to use in functional assays. -
Clonality
Monoclonal -
Clone number
TB21 -
Myeloma
Sp2/0-Ag14 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
