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Biochemicals Product Range New

Pitstop® 2-100, clathrin terminal domain inhibitor (ab144650)

Price and availability

144 067 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Novel clathrin terminal domain inhibitor
  • Purity: > 99%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Pitstop® 2-100, clathrin terminal domain inhibitor
  • Description

    Novel clathrin terminal domain inhibitor
  • Biological description

    Novel clathrin terminal domain inhibitor (IC50 = 7.5 μM). Specifically inhibits the internalisation of major histocompatibility complex 1 (MHC1). Related products Pitstop® 2 (ab120687), Pitstop® 1 (ab120686) and Pitstop® 1-25 (ab144651).

  • Purity

    > 99%
  • General notes

    Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (Z)-N-[5-(3,5-Dichlorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl]naphthalene-1-sulfonamide
  • Molecular weight

    463.35
  • Molecular formula

    C20H12Cl2N2O3S2
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=C4N=C(NS(=O)(=O)c2cccc1ccccc12)S\C4=C/c3cc(Cl)cc(Cl)c3
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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