Dorsomorphin (Compound C) (DMSO solution), AMP-kinase inhibitor (ab146597)
Key features and details
- Potent, selective and reversible AMP-kinase inhibitor. Selective for BMP signaling.
- CAS Number: 866405-64-3
- Purity: > 99%
- Supplied in DMSO (10mM)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dorsomorphin (Compound C) (DMSO solution), AMP-kinase inhibitor -
Description
Potent, selective and reversible AMP-kinase inhibitor. Selective for BMP signaling. -
Biological description
Potent, selective and reversible inhibitor of AMP-kinase (Ki = 109 nM). Inhibits AMPK activation induced by AICAR (ab120358) and metformin (ab120847). Selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Does not affect ZAPK, SYK, PKCθ, PKA and JAK3. Cell-permeable.
Also available in a water soluble form (dorsomorphin dihydrochloride - ab144821)
Also available as a solid (ab120843). -
Purity
> 99% -
General notes
A natural process can cause the product to crystallize out of solution. Should it happen, it is advised to heat the solution to approximately 55°C and let it cool down before use.
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CAS Number
866405-64-3 -
Chemical structure
