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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant Human ARMET/ARP protein (ab268741)

Recombinant Human ARMET/ARP protein (ab268741)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: = 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human ARMET/ARP protein
    See all ARMET/ARP proteins and peptides
  • Purity

    = 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P55145
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
    • Molecular weight information

      18.4 kDa by SDS-PAGE
    • Amino acids

      25 to 182
  • Specifications

    Our Abpromise guarantee covers the use of ab268741 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituent: 100% PBS

      Lyophilized from 0.2 µm filtered solution.

    • Reconstitution
      A quick spin of the vial followed by reconstitution in in PBS at 200 µg/mL. Upon reconstitution, this cytokine can be stored in working aliquots at 2°-8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

    General Info

    • Alternative names

      • Arginine rich mutated in early stage tumors
      • Arginine rich protein
      • Arginine-rich protein
      • ARMET
      • ARMET protein
      • ARP
      • Manf
      • MANF_HUMAN
      • Mesencephalic astrocyte derived neurotrophic factor
      • Mesencephalic astrocyte-derived neurotrophic factor
      • MGC142148
      • MGC142150
      • Protein ARMET
      see all
    • Function

      Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
    • Sequence similarities

      Belongs to the ARMET family.
    • Domain

      The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
    • Post-translational
      modifications

      May contain sialic acid residues.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P55145 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant human ARMET/ARP protein (ab268741)
    SDS-PAGE - Recombinant human ARMET/ARP protein (ab268741)

    SDS-PAGE analysis of ab268741.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab268741? Please let us know so that we can cite the reference in this datasheet.

    ab268741 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Arginine rich mutated in early stage tumors
    • Arginine rich protein
    • Arginine-rich protein

    Images

    • SDS-PAGE - Recombinant human ARMET/ARP protein (ab268741)
      SDS-PAGE - Recombinant human ARMET/ARP protein (ab268741)

      SDS-PAGE analysis of ab268741.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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