Probenecid, ABC-transporter inhibitor (ab145725)
Key features and details
- ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker.
- CAS Number: 57-66-9
- Purity: > 99%
- Soluble in ethanol to 75 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Probenecid, ABC-transporter inhibitor -
Description
ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker. -
Biological description
ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC50 = 150 μM). Can be used to block the efflux of intracellular dyes and indicators. -
Purity
> 99% -
CAS Number
57-66-9 -
Chemical structure
Properties
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Chemical name
4-[(Dipropylamino)sulfonyl]benzoic acid -
Molecular weight
285.36 -
Molecular formula
C13H19NO4S -
PubChem identifier
4911 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 75 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O -
Source
Synthetic
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Research areas
