Recombinant human 2B4 protein (Fc Chimera Active) (ab185251)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Tags: Fc tag C-Terminus
- Suitable for: SDS-PAGE, ELISA
Preparation and Storage
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Alternative names
- 2B4
- C9.1
- CD244
see all -
Function
Modulate other receptor-ligand interactions to enhance leukocyte activation. -
Tissue specificity
Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. -
Sequence similarities
Contains 2 Ig-like (immunoglobulin-like) domains. -
Cellular localization
Membrane. - Information by UniProt
Images
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Immobilized Hab185251 at 2 μg/mL (100 μL/well) can bind Human CD48, Mouse IgG2a Fc Tag with a linear range of 2-16 ng/mL.
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Human 2B4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The protein migrates as 60-80 kDa due to glycosylation.