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Immunology Innate Immunity NK Cells

Recombinant human 2B4 protein (BSA and azide free) (ab185248)

Recombinant human 2B4 protein (BSA and azide free) (ab185248)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Tags: His tag C-Terminus
  • Suitable for: Functional Studies, SDS-PAGE

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Preparation and Storage

  • Alternative names

    • 2B4
    • C9.1
    • CD244
    • CD244 antigen
    • CD244 molecule
    • CD244 molecule natural killer cell receptor 2B4
    • CD244 natural killer cell receptor 2B4
    • CD244_HUMAN
    • F730046O15Rik
    • h2B4
    • Ly90
    • NAIL
    • Natural killer cell activation-inducing ligand
    • Natural killer cell receptor 2B4
    • NK cell activation inducing ligand
    • NK cell activation inducing ligand NAIL
    • NK cell activation-inducing ligand
    • NK cell type I receptor protein 2B4
    • NKR2B4
    • Nmrk
    • Non-MHC restricted killing associated
    • OTTHUMP00000027884
    • p38
    • signaling lymphocytic activation molecule 4
    • SLAM family, member 4
    • SLAMF4
    see all
  • Function

    Modulate other receptor-ligand interactions to enhance leukocyte activation.
  • Tissue specificity

    Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.
  • Sequence similarities

    Contains 2 Ig-like (immunoglobulin-like) domains.
  • Cellular localization

    Membrane.
  • Target information above from: UniProt accession Q9BZW8 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant human 2B4 protein (BSA and azide free) (ab185248)
    SDS-PAGE - Recombinant human 2B4 protein (BSA and azide free) (ab185248)

    SDS-PAGE analysis of ab185248 in reducing conditions. Gel stained overnight with Coomassie Blue. DTT-reduced protein migrates as 40-50 kDa due to glycosylation.

  • Functional Studies - Recombinant human 2B4 protein (BSA and azide free) (ab185248)
    Functional Studies - Recombinant human 2B4 protein (BSA and azide free) (ab185248)

    Immobilized Recombinant human 2B4 protein (ab185248) at 5 μg/mL (100 μL/well) can bind Human CD48, Fc Tag with a linear range of 0.078-1.25 μg/mL.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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