Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator (ab145871)
Key features and details
- Cell-permeable non-toxic hydrazone iron chelator
- CAS Number: 737-86-0
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator -
Description
Cell-permeable non-toxic hydrazone iron chelator -
Alternative names
- PIH
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Biological description
Cell-permeable non-toxic hydrazone iron chelator. Prevents iron-mediated oxyradical formation and minimizes tissue damage. Anticancer and apoptotic agent. Active in vitro.
See similar compounds -
Purity
> 99% -
CAS Number
737-86-0 -
Chemical structure
Properties
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Chemical name
2-[[3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide 4-pyridinecarboxylic acid -
Molecular weight
286.29 -
Molecular formula
C14H14N4O3 -
PubChem identifier
135409539 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=NC=C(C(=C1O)/C=N/NC(=O)C2=CC=NC=C2)CO -
Source
Synthetic
