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Cancer Drug resistance Topoisomerases

Piperlongumine, alkaloid from Piper longum L. (ab141468)

Key features and details

  • Constituent of Piper longum. Shows antitumor activity.
  • CAS Number: 20069-09-4
  • Purity: > 97%
  • Soluble in DMSO to 75 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Piperlongumine, alkaloid from Piper longum L.
  • Description

    Constituent of Piper longum. Shows antitumor activity.
  • Biological description

    Constituent of Piper longum. Increases levels of ROS° and apoptosis. Shows antitumor and antiproliferative activity.
  • Purity

    > 97%
  • CAS Number

    20069-09-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[(E)-3-(3,4,5-Trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one
  • Molecular weight

    317.34
  • Molecular formula

    C17H19NO5
  • PubChem identifier

    637858
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Synthesis
    • Topoisomerases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Nitric oxide & oxidative stress
    • ROS
    • Biochemicals
    • Research Area
    • Cancer
    • Signal transduction
    • Nitric oxide & oxidative stress
    • ROS

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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