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PD 184352 (CI-1040) (DMSO solution), MEK1/2 inhibitor (ab146601)

Price and availability

117 264 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Potent, highly selective ATP non-competitive MEK1/2 inhibitor
  • CAS Number: 212631-79-3
  • Purity: > 99%
  • Supplied in DMSO (10 mM)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    PD 184352 (CI-1040) (DMSO solution), MEK1/2 inhibitor
  • Description

    Potent, highly selective ATP non-competitive MEK1/2 inhibitor
  • Biological description

    Potent, highly selective ATP non-competitive MEK1/2 inhibitor. Enhances cisplatin (ab141398) dependent apoptosis. Shows antitumor effects in vivo. Orally active.

    Also available as a solid (ab141348).

  • Purity

    > 99%
  • CAS Number

    212631-79-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(2-Chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
  • Molecular weight

    478.67
  • Molecular formula

    C17H14ClF2IN2O2
  • PubChem identifier

    6918454
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    c1cc(c(cc1I)Cl)Nc2c(ccc(c2F)F)C(=O)NOCC3CC3
  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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