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NAN-190 hydrobromide, 5-HT1A antagonist (ab120543)

Price and availability

214 425 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Potent 5-HT1A antagonist
  • CAS Number: 115388-32-4
  • Purity: > 99%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    NAN-190 hydrobromide, 5-HT1A antagonist
  • Description

    Potent 5-HT1A antagonist
  • Biological description

    Potent 5-HT1A receptor antagonist (Ki = 6.8 nM). Also displays activity at α2 adrenoceptors. Displays anxiogenic and anxiolytic effects. Additionally, potentiates circadian rhythm response to light.

  • Purity

    > 99%
  • CAS Number

    115388-32-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide
  • Molecular weight

    474.40
  • Molecular formula

    C23H27N3O3.HBr
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Adrenergic Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Serotonin Receptors
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adrenoceptors
    • α
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Serotonin
    • 5-HT1
    • 5-HT1A
    • Antagonists
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Depression
    • Serotonin
    • 5-HT1
    • 5HT1A
    • Antagonists
    • Biochemicals
    • Research Area
    • Heart disease
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Heart disease
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Hypertension
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Hypertension
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Obesity
    • Serotonin
    • 5-HT1
    • 5HT1A
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Serotonin
    • 5-HT1
    • 5HT1A
    • Antagonists
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Serotonin
    • 5-HT1
    • 5HT1A
    • Antagonists
    • Biochemicals
    • Research Area
    • Stress / Anxiety
    • Adrenoceptors
    • α
    • Biochemicals
    • Research Area
    • Stress / Anxiety
    • Adrenoceptors
    • α
    • α2
    • Antagonists
    • Biochemicals
    • Research Area
    • Stress / Anxiety
    • Serotonin
    • 5-HT1
    • 5HT1A
    • Antagonists

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