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MK2 Kinase Inhibitor, Hsp25 Kinase (MAPKAP kinase-2) inhibitor (ab146422)

Key features and details

  • Selective Hsp25 Kinase (MAPKAP kinase-2) inhibitor
  • CAS Number:
  • Purity: > 95%
  • Soluble in water
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    MK2 Kinase Inhibitor, Hsp25 Kinase (MAPKAP kinase-2) inhibitor
  • Description

    Selective Hsp25 Kinase (MAPKAP kinase-2) inhibitor
  • Alternative names

    • Hsp25 Kinase Inhibitor
    • KKKALNRQLGVAA
    • MAPKAP Kinase-2 Inhibitor
    • MAPKII Kinase Inhibitor
    • MK2 Inhibitor
    see all
  • Biological description

    13-residue peptide that acts as a selective inhibitor of mammalian heat-shock protein (Hsp25) kinase [mitogen-activated protein kinase-activated protein kinase-2 (MAPKAP kinase-2)]. Inhibition is competitive with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM).

  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    1396.70
  • Molecular formula

    C61H113N21O16
  • Sequence

    KKKALNRQLGVAA
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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