Mertansine (DM1 Compound), microtubule-targeted cytotoxic agent (ab146096)
Key features and details
- Potent microtubule-targeted cytotoxic agent
- CAS Number: 139504-50-0
Slightly soluble in Chloroform and Methanol.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mertansine (DM1 Compound), microtubule-targeted cytotoxic agent -
Description
Potent microtubule-targeted cytotoxic agent -
Alternative names
- DM1 Compound
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Biological description
Potent microtubule-targeted cytotoxic agent. Induces mitotic arrest. Inhibits microtubule polymerization. Shows antitumor effects in vivo. -
CAS Number
139504-50-0 -
Chemical structure
Properties
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Chemical name
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine
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Molecular weight
738.29 -
Molecular formula
C35H48ClN3O10S -
PubChem identifier
71301226 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Slightly soluble in Chloroform and Methanol.
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic. Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(\CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@H]([C@]4(C1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCS)C)/C)OC)(NC(=O)O2)O -
Source
Synthetic
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Research areas
