CRANAD-2, Near-infrared Amyloid-beta fluorescent probe (ab141775)
Key features and details
- Near-infrared Amyloid-β fluorescent probe
- CAS Number: 1193447-34-5
- Purity: > 98%
- Soluble in DMSO to 5 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CRANAD-2, Near-infrared Amyloid-beta fluorescent probe -
Description
Near-infrared Amyloid-β fluorescent probe -
Alternative names
- CRANAD 2
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Biological description
Near-infrared (NIR) Amyloid-β fluorescent probe. Upon interacting with Amyloid-β aggregates displays a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm. Demonstrates high affinity for amyloid-β aggregates (Kd = 38 nM). Detects amyloid-β in vitro and in vivo. Blood-brain barrier permeable. Learn more
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Purity
> 98% -
CAS Number
1193447-34-5 -
Chemical structure
Properties
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Chemical name
(T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-
dionato-kO3,kO5]difluoroboron -
Molecular weight
410.27 -
Molecular formula
C23H25BF2N2O2 -
PubChem identifier
90488972 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 5 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[B-]1(OC(=C/C(=C/C=C2C=CC(=[N+](C)C)C=C2)/O1)/C=C/C3=CC=C(C=C3)N(C)C)(F)F -
Source
Synthetic
