Ferutinin, ERalpha agonist (ab144254)
Key features and details
- Potent ERα agonist and ERβ agonist / antagonist
- CAS Number: 41743-44-6
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ferutinin, ERalpha agonist -
Description
Potent ERα agonist and ERβ agonist / antagonist -
Biological description
Potent ERα agonist and ERβ agonist / antagonist (IC50 values are 33 and 181 nM for ERα and ERβ respectively). Increases calcium permeability in the lipid bilayer. Induces apoptosis. Shows selective cytotoxic effects to tumor cells. Shows chemopreventive and anticancer effects in vivo. -
Purity
> 98% -
CAS Number
41743-44-6 -
Chemical structure
Properties
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Chemical name
[(3R,3aS,4S,8aR)-3-Hydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl] 4-hydroxybenzoate -
Molecular weight
358.47 -
Molecular formula
C22H30O4 -
PubChem identifier
354654 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC[C@]2(CC[C@]([C@@H]2[C@H](C1)OC(=O)C3=CC=C(C=C3)O)(C(C)C)O)C -
Source
Synthetic
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Research areas
