ME 0328, PARP-3 inhibitor (ab146150)
Key features and details
- Cell-permeable, selective PARP-3 inhibitor
- CAS Number: 1445251-22-8
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ME 0328, PARP-3 inhibitor -
Description
Cell-permeable, selective PARP-3 inhibitor -
Biological description
Cell-permeable, selective PARP-3 inhibitor (IC50 values are 0.89, 6.3, 10.8 and >30 μM for PARP-3, PARP-1, PARP-2 and other ARDT enzymes respectively). Metabolically stable in human liver microsomes and rat hepatocytes. -
CAS Number
1445251-22-8 -
Chemical structure
Properties
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Chemical name
3-(4-Oxo-1H-quinazolin-2-yl)-N-[(1S)-1-phenylethyl]propanamide -
Molecular weight
321.37 -
Molecular formula
C19H19N3O2 -
PubChem identifier
71571526 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H](C1=CC=CC=C1)NC(=O)CCC2=NC(=O)C3=CC=CC=C3N2 -
Source
Synthetic
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Research areas
