MCAAD-3, Near-infrared probe for imaging of amyloid plaques (ab216983)
Key features and details
- Near-infrared probe for imaging of amyloid plaques in Alzheimer's disease
- CAS Number: 1625629-51-7
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MCAAD-3, Near-infrared probe for imaging of amyloid plaques -
Description
Near-infrared probe for imaging of amyloid plaques in Alzheimer's disease -
Biological description
Near-infrared probe for imaging of amyloid plaques in Alzheimer's disease. DANIR 2c analog that shows extended emission wavelength and significant reduced binding affinity to Aβ aggregates compared with DANIR 2c. In vivo imaging studies suggest that MCAAD-3 can penetrate the blood–brain barrier and label Aβ plaques in the brains of transgenic mice. Learn more
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Purity
> 99% -
CAS Number
1625629-51-7 -
Chemical structure
Properties
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Chemical name
methyl (2Z,4E,6E)-2-cyano-7-[4-(dimethylamino)]hepta-2,4,6-trienoate -
Molecular weight
282.34 -
Molecular formula
C17H18N2O2 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)c1ccc(/C=C/C=C/C=C(/C#N)C(=O)OC)cc1 -
Source
Synthetic
