IB-MECA, A3 agonist (ab120438)
Key features and details
- Highly potent and selective A3 agonist
- CAS Number: 152918-18-8
- Purity: > 97%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IB-MECA, A3 agonist -
Description
Highly potent and selective A3 agonist -
Biological description
Highly potent and selective A3 agonist (Ki values are 1.1, 12.6 and 56 nM at A3, A1 and A2A receptors, respectively). Produces potent cardioprotective effects against myocardial injury. Mediates suppression of melanoma cells and suppresses human breast cancer cell proliferation.
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Purity
> 97% -
CAS Number
152918-18-8 -
Chemical structure
Properties
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Chemical name
1-Deoxy-1-[6-[[(3-Iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide -
Molecular weight
510.29 -
Molecular formula
C18H19IN6O4 -
PubChem identifier
123683 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Ic1cccc(c1)CNc4ncnc3c4ncn3[C@@H]2O[C@@H]([C@H](O)C2O)C(=O)NC -
Source
Synthetic
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Research areas