• Product name

  Human Apolipoprotein B peptide
  See all Apolipoprotein B proteins and peptides

• Animal free

  No

• Nature

  Synthetic

• • Species

    Human

• Alternative names

  • Apo B
  • Apo B 100
  • Apo B-100

  • Apo B-48
  • Apo B100
  • Apo B48
  • APOB
  • ApoB 100
  • ApoB 48
  • APOB_HUMAN
  • Apolipoprotein B
  • Apolipoprotein B (including Ag(x) antigen)
  • Apolipoprotein B 100
  • Apolipoprotein B 48
  • Apolipoprotein B-48
  • Apolipoprotein B100
  • Apolipoprotein B48
  • FLDB
  • LDLCQ4

  see all

• Function

  Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

• Involvement in disease

  Hypobetalipoproteinemia, familial, 1
  Familial ligand-defective apolipoprotein B-100
  Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.

• Sequence similarities

  Contains 1 vitellogenin domain.

• Post-translational
  modifications

  Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.

• Cellular localization

  Cytoplasm. Secreted.

• Target information above from: UniProt accession P04114 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt