GM 6001, MMP inhibitor (DMSO solution) (ab147470)
Key features and details
- Broad spectrum MMP inhibitor
- CAS Number: 142880-36-2
- Purity: > 98%
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
GM 6001, MMP inhibitor (DMSO solution) -
Description
Broad spectrum MMP inhibitor -
Alternative names
- Galardin
- ilomastat
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Biological description
Broad spectrum potent MMP inhibitor. Ki values are 0.4 (MMP-1), 0.5 (MMP-2), 27 (MMP-3), 0.1 (MMP-8), 0.2 (MMP-9), 13.4 (MMP-14) and 0.36 (MMP-26) nM. IC50 value for MMP-7 is 3.7 nM. Pharmacologically active in vivo.
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Purity
> 98% -
CAS Number
142880-36-2 -
Chemical structure
Properties
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Chemical name
(2R)-N4-Hydroxy-N1-[(1S)-2-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)butanediamide -
Molecular weight
388.47 -
Molecular formula
C20H28N4O4 -
PubChem identifier
132519 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ONC(=O)C[C@@H](CC(C)C)C(=O)N[C@@H](Cc2cnc1ccccc12)C(=O)NC -
Source
Synthetic