Glimepiride, cardiac KATP channel blocker (ab142301)
Key features and details
- Potent cardiac KATP channel blocker
- CAS Number: 93479-97-1
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Glimepiride, cardiac KATP channel blocker -
Description
Potent cardiac KATP channel blocker -
Biological description
Potent cardiac Kir6 (KATP) channel blocker (IC50 = 6.8 nM). Antidiabetic agent. Orally active and active in vivo. -
Purity
> 98% -
CAS Number
93479-97-1 -
Chemical structure
Properties
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Chemical name
4-Ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide -
Molecular weight
490.62 -
Molecular formula
C24H34N4O5S -
PubChem identifier
3476 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C -
Source
Synthetic
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Research areas