Furafylline, PDE inhibitor (ab146021)
Key features and details
- PDE inhibitor. Selective cytochrome P450IA2 inhibitor. Methyl xanthine derivative.
- CAS Number: 80288-49-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Furafylline, PDE inhibitor -
Description
PDE inhibitor. Selective cytochrome P450IA2 inhibitor. Methyl xanthine derivative. -
Biological description
PDE inhibitor. Selective cytochrome P450IA2 inhibitor (IC50 = 2.4 μM). Methyl xanthine derivative. Shows an expanded duration of action compared to theophylline (ab142599) in vivo. Orally active.
-
Purity
> 98% -
CAS Number
80288-49-9 -
Chemical structure
Properties
-
Chemical name
3-(2-Furanylmethyl)-3,9-dihydro-1,8-dimethyl-1H-purine-2,6-dione -
Molecular weight
260.25 -
Molecular formula
C12H12N4O3 -
PubChem identifier
3433 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=NC2=C(N1)C(=O)N(C(=O)N2CC3=CC=CO3)C -
Source
Synthetic
-
Research areas
