FITC Anti-Integrin beta 3 antibody [HM beta 3.1] (ab36437)
![FITC Anti-Integrin beta 3 antibody [HM beta 3.1] (ab36437)](https://www.abcam.com/ps/products/36/ab36437/Images/ab36437-218570-ab36437.jpg "FITC Anti-Integrin beta 3 antibody [HM beta 3.1] (ab36437)")
Key features and details
- FITC Armenian hamster monoclonal [HM beta 3.1] to Integrin beta 3
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Overview
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Product name
FITC Anti-Integrin beta 3 antibody [HM beta 3.1]
See all Integrin beta 3 primary antibodies -
Description
FITC Armenian hamster monoclonal [HM beta 3.1] to Integrin beta 3 -
Host species
Armenian hamster -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
Recognises the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. -
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Mouse
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Immunogen
Tissue, cells or virus corresponding to Mouse Integrin beta 3. Mouse integrin alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
Database link: O54890 -
General notes
Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin.
Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
Purified from tissue culture supernatant. -
Primary antibody notes
Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. -
Clonality
Monoclonal -
Clone number
HM beta 3.1 -
Isotype
IgG -
Research areas
Images
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Flow Cytometry - FITC Anti-Integrin beta 3 antibody [HM beta 3.1] (ab36437)
Staining of mouse peripheral blood platelets with ab36437.
