BCTC, inhibitor of TRPV1 (ab141517)
Key features and details
- Potent inhibitor of TRPV1
- CAS Number: 393514-24-4
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BCTC, inhibitor of TRPV1 -
Description
Potent inhibitor of TRPV1 -
Biological description
Potent inhibitor of TRPV1 (IC50 values are 35 and 6 nM for capsaicin and acid-induced activation respectively). Inhibits TRPM8 (IC50 = 0.8 μM). Reduces hyperalgesia in vivo. -
Purity
> 98% -
CAS Number
393514-24-4 -
Chemical structure
Properties
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Chemical name
N-(4-tert-Butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide -
Molecular weight
372.90 -
Molecular formula
C20H25ClN4O -
PubChem identifier
9929425 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl -
Source
Synthetic
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Research areas
