ML297 (VU0456810), GIRK activator (ab143564)
Key features and details
- Potent, selective GIRK activator
- CAS Number:
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML297 (VU0456810), GIRK activator -
Description
Potent, selective GIRK activator -
Biological description
Potent, selective GIRK activator (EC50 = 160 nM). Shows anticonvulsant effects in vivo.
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Purity
> 99% -
Chemical structure
Properties
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Chemical name
1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea -
Molecular weight
328.32 -
Molecular formula
C17H14F2N4O -
PubChem identifier
56642816 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Fc1ccc(cc1F)NC(=O)Nc3cc(C)nn3c2ccccc2 -
Source
Synthetic
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Research areas