Anti-p55/DCAF1 antibody (ab1766)
Key features and details
- Rabbit polyclonal to p55/DCAF1
- Isotype: IgG
Overview
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Product name
Anti-p55/DCAF1 antibody -
Description
Rabbit polyclonal to p55/DCAF1 -
Host species
Rabbit -
Species reactivity
Predicted to work with: Chicken, Xenopus laevis, Zebrafish -
Immunogen
Synthetic peptide:
CNVYNDEEPEIPASELETNTA
, corresponding to amino acids 411-430 of Drosophilia melanogaster CAF 1 (DCAF 1). -
General notes
Complex that assembles histone octamers onto replicating DNA in vitro. Caf-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones h3 and h4 to replicating DNA; histones H2a/H2b can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. P150 and p60 form complexes with newly synthesized histones h3 and acetylated H4 in cell extracts (by similarity). P55 associates with acetyltransferases and deacetylases in cell extracts and is also a component of the nucleosome remodeling factor complex (NURF), a protein complex consisting of four polypeptides that facilitates the perturbation of chromatin structure in vitro in an ATP-dependent manner. This subunit may assist targeting of protein complexes to chromatin.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide -
Concentration information loading...
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Purity
Whole antiserum -
Primary antibody notes
Complex that assembles histone octamers onto replicating DNA in vitro. Caf-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones h3 and h4 to replicating DNA; histones H2a/H2b can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. P150 and p60 form complexes with newly synthesized histones h3 and acetylated H4 in cell extracts (by similarity). P55 associates with acetyltransferases and deacetylases in cell extracts and is also a component of the nucleosome remodeling factor complex (NURF), a protein complex consisting of four polypeptides that facilitates the perturbation of chromatin structure in vitro in an ATP-dependent manner. This subunit may assist targeting of protein complexes to chromatin. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas