Anti-Influenza A Virus M2 Protein antibody [14C2] (ab5416)
![Anti-Influenza A Virus M2 Protein antibody [14C2] (ab5416)](https://www.abcam.com/ps/datasheet/Images/5/ab5416/ab5416_1.jpg "Anti-Influenza A Virus M2 Protein antibody [14C2] (ab5416)")
Key features and details
- Mouse monoclonal [14C2] to Influenza A Virus M2 Protein
- Suitable for: Inhibition Assay, Flow Cyt, ICC/IF, ICC, IP, WB
- Reacts with: Dog, Influenza A
- Isotype: IgG1
Overview
-
Product name
Anti-Influenza A Virus M2 Protein antibody [14C2]
See all Influenza A Virus M2 Protein primary antibodies -
Description
Mouse monoclonal [14C2] to Influenza A Virus M2 Protein -
Host species
Mouse -
Tested applications
Suitable for: Inhibition Assay, Flow Cyt, ICC/IF, ICC, IP, WBmore details -
Species reactivity
Reacts with: Dog, Influenza A -
Immunogen
Tissue, cells or virus corresponding to Influenza A Virus M2 Protein. Full length M2 protein from A/WSN/33-infected CV1 cell lysate.
-
Epitope
Detects the N-terminal of the Influenza A Virus M2 Protein. -
Positive control
- ICC/IF: Infected MDCK cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Primary antibody notes
Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2). M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA. M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain. The M2 protein has been found to play a role in Influenza replication and assembly of virion particles. Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication. -
Clonality
Monoclonal -
Clone number
14C2 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Images
-
Immunocytochemistry/ Immunofluorescence - Anti-Influenza A Virus M2 Protein antibody [14C2] (ab5416)Immunofluorescence staining of infected MDCK cells using ab5416.