Anti-Apolipoprotein A I antibody (ab7614)
Key features and details
- Goat polyclonal to Apolipoprotein A I
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Apolipoprotein A I antibody
See all Apolipoprotein A I primary antibodies -
Description
Goat polyclonal to Apolipoprotein A I -
Host species
Goat -
Specificity
Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA. This antibody reacts with mouse apoLipoprotein A-I and has negligible cross-reactivity with Type A-II, B, C-I, C-II, C-III, E and J apoLipoproteins. -
Species reactivity
Reacts with: Mouse -
Immunogen
Full length native apoLipoprotein Type A-I (purified).
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General notes
This antibody has been used to determine that atherosclerotic lesions in the human aorta contain considerable amounts of lipoproteins. These lipoproteins were observed to be complexed with components of the extracellular matrix (especially LDL and proteoglycans). The role of these matrix-lipoprotein complexes is not entirely clear, however, animal models of atherosclerosis have shown that increased cellular proliferation and increased production of extracellular matrix components occur following injury to the intimal layer of the aorta.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.44% Sodium chloride, 4.77% Sodium borate, 0.15% EDTA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
