680C91, tryptophan 2,3-dioxygenase inhibitor (ab146153)
Key features and details
- Potent, selective, substrate competitive tryptophan 2,3-dioxygenase inhibitor
- CAS Number: 163239-22-3
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
680C91, tryptophan 2,3-dioxygenase inhibitor -
Description
Potent, selective, substrate competitive tryptophan 2,3-dioxygenase inhibitor -
Biological description
Potent, selective, substrate competitive tryptophan 2,3-dioxygenase inhibitor (Ki = 51 nM). Inhibits tryptophan catabolism. Increases brain tryptophan and serotonin levels in vivo. -
CAS Number
163239-22-3 -
Chemical structure
Properties
-
Chemical name
6-Fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indole -
Molecular weight
238.26 -
Molecular formula
C15H11FN2 -
PubChem identifier
10014426 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1=CC(=CN=C1)/C=C/C2=CNC3=C2C=CC(=C3)F -
Source
Synthetic
-
Research areas