24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite (ab141633)
Key features and details
- Endogenous cholesterol metabolite
- CAS Number: 77058-74-3
- Purity: > 95%
- Soluble in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
24(S),25-Epoxycholesterol, Endogenous cholesterol metabolite -
Description
Endogenous cholesterol metabolite -
Biological description
Endogenous cholesterol metabolite. Suppresses SREBP activation in the regulation of hepatic cholesterol metabolism in vivo.
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Purity
> 95% -
General notes
We recommend immediate use of this product following dissolution.
Although reported to be soluble in DMSO our analysis shows gentle heating is required to achieve this, leading to significant decomposition. The product is soluble in ethanol, however we found extended time or gentle warming once again led to some degree of decomposition. -
CAS Number
77058-74-3 -
Chemical structure
Properties
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Chemical name
(3β,24S)-24,25-Epoxycholest-5-en-3-ol -
Molecular weight
400.64 -
Molecular formula
C27H44O2 -
PubChem identifier
3247059 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 25 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CCC1C(O1)(C)C)C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)O)C)C -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
