2-Acetyl-4-(1(R),2(S),3(R),4-tetrahydroxybutyl)imidazole, sphingosine-1-phosphate lyase inhibitor (ab144103)
Key features and details
- Inhibitor of sphingosine-1-phosphate lyase
- CAS Number: 94944-70-4
- Purity: > 99%
- Soluble in water and in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Acetyl-4-(1(R),2(S),3(R),4-tetrahydroxybutyl)imidazole, sphingosine-1-phosphate lyase inhibitor -
Description
Inhibitor of sphingosine-1-phosphate lyase -
Alternative names
- 2-Acetyl-4-tetrahydroxybutylimidazole
- 2-ATHBI
- THI
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Biological description
Inhibitor of sphingosine-1-phosphate lyase. Induces lymphopenia, affects lymphocyte migration and degradation. Immunosuppressive potential. Use in sphingolipid studies. Active in vivo. -
Purity
> 99% -
CAS Number
94944-70-4 -
Chemical structure
Properties
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Chemical name
1-[5-[(1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl]-1H-imidazol-2-yl]ethanone -
Molecular weight
230.22 -
Molecular formula
C9H14N2O5 -
PubChem identifier
108037 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water and in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)C1=NC=C(N1)[C@H]([C@@H]([C@@H](CO)O)O)O -
Source
Synthetic
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Research areas
