TG003, ATP-competitive Clk1/Sty inhibitor (ab141463)
Key features and details
- Potent, selective ATP-competitive Clk1/Sty inhibitor
- CAS Number: 300801-52-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TG003, ATP-competitive Clk1/Sty inhibitor -
Description
Potent, selective ATP-competitive Clk1/Sty inhibitor -
Biological description
Potent, selective ATP-competitive Clk1/Sty inhibitor (IC50 values are 20, 200, 15 nM and >10 μM for Clk1/Sty, Clk2, Clk4 and Clk3 respectively). Blocks alternative splicing of PKCβII and expression of PPARγ1 and PPARγ2. Shows analgesic effects in vivo. Centrally active. -
Purity
> 98% -
CAS Number
300801-52-9 -
Chemical structure
