StemRegenin 1 hydrochloride, AhR antagonist (ab142174)
Key features and details
- Cell-permeable, potent AhR antagonist
- CAS Number: 1227633-49-9
- Purity: > 98%
- Soluble in DMSO to 100 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
StemRegenin 1 hydrochloride, AhR antagonist -
Description
Cell-permeable, potent AhR antagonist -
Biological description
Cell-permeable, potent aryl hydrocarbon receptor antagonist (IC50 = 127 nM). Used for hematopoietic differentiation of iPSCs. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
1227633-49-9 -
Chemical structure
Properties
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Chemical name
4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol hydrochloride -
Molecular weight
466.00 -
Molecular formula
C24H23N5OS.HCl -
PubChem identifier
46199207 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Oc1ccc(cc1)CCNc3nc(nc2c3ncn2C(C)C)c5csc4ccccc45 -
Source
Synthetic
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Research areas
