SCD1 Inhibitor, SCD1(stearoyl-CoA desaturase 1) inhibitor (ab142089)
Key features and details
- Potent, selective SCD1(stearoyl-CoA desaturase 1) inhibitor
- CAS Number: 1032229-33-6
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SCD1 Inhibitor, SCD1(stearoyl-CoA desaturase 1) inhibitor -
Description
Potent, selective SCD1(stearoyl-CoA desaturase 1) inhibitor -
Biological description
Potent, selective SCD1 (stearoyl-CoA desaturase 1) inhibitor (IC50 = 4.5 nM). Inhibits the conversion of saturated, long-chain fatty acyl-CoAs to monounsaturated, long-chain fatty acyl-CoAs in vitro, when heptadecanoic acid and palmitic acid are used as the substrate (IC50 = 7.9 and 6.8 nM, respectively). Active in vivo. Orally bioavailable.
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Purity
> 99% -
CAS Number
1032229-33-6 -
Chemical structure
Properties
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Chemical name
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide -
Molecular weight
387.87 -
Molecular formula
C20H22ClN3O3 -
PubChem identifier
24905400 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CNC(=O)C1=CC(=CC=C1)NC(=O)N2CCC(CC2)OC3=CC=CC=C3Cl -
Source
Synthetic
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Research areas