SC-51322, EP1 receptor antagonist (ab141738)
Key features and details
- Potent, selective EP1 receptor antagonist
- CAS Number: 146032-79-3
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SC-51322, EP1 receptor antagonist -
Description
Potent, selective EP1 receptor antagonist -
Biological description
Potent, selective EP1 receptor antagonist (Ki values are 13.8 and 698 nM for EP1 and EP3 receptors respectively). One hundred times more potent than SC-51089. Potentiates PGE2 induced vascular relaxation and has analgesic activity. Active in vitro and centrally active in vivo. -
Purity
> 98% -
CAS Number
146032-79-3 -
Chemical structure
Properties
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Chemical name
3-Chloro-N'-[3-(furan-2-ylmethylsulfanyl)propanoyl]-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide -
Molecular weight
457.90 -
Molecular formula
C22H20ClN3O4S -
PubChem identifier
9933831 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C2=CC=CC=C2OC3=C(N1C(=O)NNC(=O)CCSCC4=CC=CO4)C=C(C=C3)Cl -
Source
Synthetic
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Research areas
