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Signal Transduction Signaling Pathway Lipid Signaling Prostaglandins

(R)-Butaprost, EP2 agonist (ab144476)

Key features and details

  • Selective EP2 agonist
  • CAS Number: 69648-38-0
  • Purity: > 98%
  • Soluble in ethanol to 100 mM and in DMSO to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    (R)-Butaprost, EP2 agonist
  • Description

    Selective EP2 agonist
  • Biological description

    Selective EP2 agonist. PGE2 structural analog. Inhibits chemotaxis (EC50 = 106 nM, maximal effect of PGE2). Increases neutrophil cyclic AMP levels.
  • Purity

    > 98%
  • CAS Number

    69648-38-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,4R)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoate
  • Molecular weight

    408.58
  • Molecular formula

    C24H40O5
  • PubChem identifier

    5311035
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 100 mM and in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCC1(CCC1)[C@@H](C/C=C/[C@H]2[C@@H](CC(=O)[C@@H]2CCCCCCC(=O)OC)O)O
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Prostaglandins
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cardiovascular
    • Vasculature
    • Vasodilation
    • Prostaglandins
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Prostanoid

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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