SB742457 (Intepirdine), 5-HT6 antagonist (ab269695)
Key features and details
- Potent and highly selective 5-HT6 antagonist
- CAS Number: 607742-69-8
Soluble in DMSO to 50 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB742457 (Intepirdine), 5-HT6 antagonist -
Description
Potent and highly selective 5-HT6 antagonist -
Alternative names
- Intepiridine
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Biological description
Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.
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CAS Number
607742-69-8 -
Chemical structure
Properties
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Chemical name
3-(Phenylsulfonyl)-8-(1-piperazinyl)-quinoline
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Molecular weight
353.44 -
Molecular formula
C19H19N3O2S -
PubChem identifier
11256720 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 5 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4 -
Source
Synthetic
Images
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Chemical Structure - SB742457 (Intepirdine), 5-HT6 antagonist (ab269695)
Chemical structure of SB742457 (Intepirdine), 5-HT6 antagonist, 607742-69-8