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Signal Transduction Cytoskeleton / ECM Extracellular Matrix ECM Enzymes MMP

SB-3CT, MMP-2 and MMP-9 inhibitor (ab141579)

Price and availability

50 256 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor
  • CAS Number: 292605-14-2
  • Purity: > 98%
  • Soluble in DMSO to 25 mM and ethanol
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SB-3CT, MMP-2 and MMP-9 inhibitor
  • Description

    Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor
  • Biological description

    Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
  • Purity

    > 98%
  • CAS Number

    292605-14-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane
  • Molecular weight

    306.40
  • Molecular formula

    C15H14O3S2
  • PubChem identifier

    9883002
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM and ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Adhesion / ECM
    • Matrix Metalloproteinases
    • MMP
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • MMP
    • Cancer
    • Invasion/microenvironment
    • Angiogenesis
    • ECM enzymes
    • MMPs
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • MMPs
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Metalloprotease
    • MMPs
    • Cancer
    • Tumor biomarkers
    • Enzymes
    • MMPs
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Other
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    • Cancer Metabolism
    • Response to hypoxia
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    • Protease
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    • Inhibitors
    • Biochemicals
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    • Extracellular matrix & cell adhesion
    • Matrix metalloprotease
    • Biochemicals
    • Research Area
    • Cancer
    • Extracellular matrix & cell adhesion
    • Matrix metalloprotease

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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