SB 203580 (DMSO solution), p38 MAPK inhibitor (ab146589)
Key features and details
- p38 MAPK inhibitor
- CAS Number: 152121-47-6
- Purity: > 98%
- Supplied in DMSO (10 mM)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB 203580 (DMSO solution), p38 MAPK inhibitor -
Description
p38 MAPK inhibitor -
Biological description
Cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1, RIP2, c-Raf and GSK3.
Also available as a solid (ab120162). -
Purity
> 98% -
CAS Number
152121-47-6 -
Chemical structure
Properties
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Chemical name
4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine -
Molecular weight
377.43 -
Molecular formula
C21H16FN3OS -
PubChem identifier
176155 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (10 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)c1ccc(cc1)c2nc(c(n2)c3ccncc3)c4ccc(F)cc4 -
Source
Synthetic
