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Epigenetics and Nuclear Signaling Transcription Domain Families Zinc Finger

(R,S)-Lenalidomide, Thalidomide analog, TNF alpha inhibitor (ab142129)

Key features and details

  • Thalidomide analog, TNF-α inhibitor
  • CAS Number: 191732-72-6
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    (R,S)-Lenalidomide, Thalidomide analog, TNF alpha inhibitor
  • Description

    Thalidomide analog, TNF-α inhibitor
  • Biological description

    Thalidomide (ab120032) analog and TNF-α inhibitor. Potent antitumor and anti-inflammatory effects. Modulates and potentiates host immune responses against multiple myeloma. Active in vitro.
  • Purity

    > 98%
  • CAS Number

    191732-72-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-(7-Amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
  • Molecular weight

    259.26
  • Molecular formula

    C13H13N3O3
  • PubChem identifier

    216326
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Transcription Factors
    • Cancer
    • Invasion/microenvironment
    • Apoptosis
    • Other
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants
    • Cancer
    • Cell Death
    • Apoptosis
    • Other

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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