Rhodol (ab275921)
Key features and details
- Highly fluorescent dye useful for labeling oligonucleotide, antibody and protein studies
- CAS Number: 3086-44-0
- Purity: > 98%
Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rhodol -
Description
Highly fluorescent dye useful for labeling oligonucleotide, antibody and protein studies -
Biological description
Highly fluorescent dye useful for labeling oligonucleotide, antibody and protein studies and for the preparation of peptide and esterase substrates.
Rhodol is a structural hybrid of fluorescein and rhodamine. It retains the pH-sensitive properties conferred by a phenolic hydroxyl group, but the amine substituent reduces the pKa values. Rhodol exhibits a high extinction coefficient (~70,000 cm-1M-1) and high quantum yield (~0.8-0.9) in aqueous solution, with absorption maxima at approximately 490 nm and emission maxima between 520 and 545 nm. As with fluorescein-based dyes, the fluorescence excitation profiles of rhodol-based dyes are pH dependent, which can be useful for ratiometric pH determinations intracellularly.
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Purity
> 98% -
CAS Number
3086-44-0 -
Chemical structure
Properties
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Chemical name
3'-Amino-6'-hydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
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Molecular weight
331.33 -
Molecular formula
C20H13NO4 -
PubChem identifier
12314937 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)N)OC5=C3C=CC(=C5)O -
Source
Synthetic
Images
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Chemical Structure - Rhodol (ab275921)
Chemical structure of Rhodol, 3086-44-0