Reticulol, Topoisomerase I inhibitor (ab144344)
Key features and details
- Topoisomerase I inhibitor. Antiproliferative agent.
- CAS Number: 26246-41-3
- Purity: > 98%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Streptomyces sp.
Overview
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Product name
Reticulol, Topoisomerase I inhibitor -
Description
Topoisomerase I inhibitor. Antiproliferative agent. -
Biological description
Topoisomerase I inhibitor. Antiproliferative agent. Inhibits cyclic adenosine 3', 5'-monophosphate phosphodiesterase. Shows necrotic effects against cancer cells. Inhibits metastasis. Shows antitumor effects in vivo. -
Purity
> 98% -
CAS Number
26246-41-3 -
Chemical structure
Properties
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Chemical name
6,8-Dihydroxy-7-methoxy-3-methylisochromen-1-one -
Molecular weight
222.19 -
Molecular formula
C11H10O5 -
PubChem identifier
5359036 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC2=CC(=C(C(=C2C(=O)O1)O)OC)O -
Source
Streptomyces sp.
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Research areas
