Recombinant SARS spike glycoprotein (Coronavirus) (ab49046)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: ELISA, WB
-
Product name
Recombinant SARS spike glycoprotein (Coronavirus)
See all SARS spike glycoprotein proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
Escherichia coli -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Tags
His tag C-Terminus -
Additional sequence information
E. coli recombinant containing Spike protein immunodominant regions Fusions Six histidines. This protein is from the Spike protein S1 region.
-
Preparation and Storage
-
Alternative names
- E2
- E2 glycoprotein
- Human coronavirus spike glycoprotein
see all -
Relevance
A novel coronavirus has been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive stranded RNA approximately 27 to 31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.
