Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Rat PLGF protein (ab190989)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Rat PLGF protein
    See all PLGF proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    The purity of ab190989 is greater than 95% by SDS-PAGE gel and HPLC analyses.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q63434

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Rat

    • Sequence

      ALSAGNNSTE MEVVPFNEVW GRSYCRPMEK LVYIADEHPN EVSHIFSPSC VLLSRCSGCC GDEGLHCVAL KTANITMQIL KIPPNRDPHS YVEMTFSQDV LCECRPILET TKAERRKTKG KRKQSKTPQT EEPHL

    • Predicted molecular weight

      30 kDa

    • Amino acids

      24 to 158

    • Additional sequence information

      ab190989 is the mature full length protein from aa 24 to 158. The signal peptide is not included. ab190989 is a 30.3 kDa disulfide-linked homodimeric protein of two 135 amino acid polypeptide chains.

    • Specifications

    Our Abpromise guarantee covers the use of ab190989 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized

    • Additional notes

      Avoid inhalation. Avoid contact with eyes, skin and clothing.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C.

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    General Info

    • Alternative names

      • D12S1900
      • Pgf
      • PGFL
      • PIGF
      • Placenta growth factor
      • Placental growth factor
      • Placental growth factor, vascular endothelial growth factor related protein
      • PlGF
      • PlGF 2
      • PLGF_HUMAN
      • PlGF2
      • SHGC 10760
      see all

    • Function

      Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner.

    • Tissue specificity

      While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.

    • Sequence similarities

      Belongs to the PDGF/VEGF growth factor family.

    • Domain

      Isoform PlGF-2 contains a basic insert which acts as a cell retention signal.

    • Post-translational
      modifications

      N-glycosylated.

    • Cellular localization

      Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab190989? Please let us know so that we can cite the reference in this datasheet.

ab190989 has not yet been referenced specifically in any publications.

Preparation and Storage

  • D12S1900
  • Pgf
  • PGFL

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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