Recombinant rat GRO gamma protein (ab201380)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, HPLC, SDS-PAGE
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Product name
Recombinant rat GRO gamma protein
See all GRO gamma proteins and peptides -
Biological activity
Fully biologically active when compared to standard.
The ED50 determined by a chemotaxis bioassay using Human CXCR2 transfected BaF3 murine proB cells is less than 20 ng/ml, corresponding to a specific activity of >5×104 IU/mg.
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Purity
> 95 % SDS-PAGE.
> 95 % by HPLC. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Rat -
Sequence
RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS -
Predicted molecular weight
8 kDa -
Amino acids
33 to 101 -
Additional sequence information
This product is for the mature full length protein. The signal peptide is not included.
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Preparation and Storage
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Alternative names
- C-X-C motif chemokine 3
- C-X-C motif chemokine ligand 3
- Chemokine (C X C motif) ligand 3
see all -
Function
Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. -
Sequence similarities
Belongs to the intercrine alpha (chemokine CxC) family. -
Post-translational
modificationsN-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
Cellular localization
Secreted. - Information by UniProt
