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Immunology Innate Immunity Chemokines Alpha Chemokines (CXC)

Recombinant human GRO gamma protein (ab9844)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant human GRO gamma protein
    See all GRO gamma proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      11 kDa
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9844 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • C-X-C motif chemokine 3
        • C-X-C motif chemokine ligand 3
        • Chemokine (C X C motif) ligand 3
        • Chemokine (CXC motif) ligand 3
        • Cinc 2
        • CINC 2b
        • Cinc2
        • CINC2b
        • CXCL 3
        • Cxcl3
        • CXCL3_HUMAN
        • Cytokine induced neutrophil chemoattractant 2
        • Dcip1
        • Dendritic cell inflammatory protein 1
        • Gm1960
        • GRO protein gamma
        • GRO-gamma
        • GRO-gamma(1-73)
        • GRO-gamma(5-73)
        • GRO3
        • GRO3 oncogene
        • GROG
        • Growth regulated protein gamma
        • Growth-regulated protein gamma
        • Macrophage inflammatory protein 2 beta precursor
        • Macrophage inflammatory protein 2-beta
        • Melanoma growth stimulatory activity gamma
        • Member 3
        • MGSA gamma
        • MIP 2b
        • MIP2-beta
        • MIP2B
        • SCYB3
        • Small inducible cytokine subfamily B
        see all
      • Function

        Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
      • Sequence similarities

        Belongs to the intercrine alpha (chemokine CxC) family.
      • Post-translational
        modifications

        N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession P19876 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab9844? Please let us know so that we can cite the reference in this datasheet.

    ab9844 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-X-C motif chemokine 3
      • C-X-C motif chemokine ligand 3
      • Chemokine (C X C motif) ligand 3
      • Chemokine (CXC motif) ligand 3
      • Cinc 2
      • CINC 2b
      • Cinc2
      • CINC2b
      • CXCL 3
      • Cxcl3
      • CXCL3_HUMAN
      • Cytokine induced neutrophil chemoattractant 2
      • Dcip1
      • Dendritic cell inflammatory protein 1
      • Gm1960
      • GRO protein gamma
      • GRO-gamma
      • GRO-gamma(1-73)
      • GRO-gamma(5-73)
      • GRO3
      • GRO3 oncogene
      • GROG
      • Growth regulated protein gamma
      • Growth-regulated protein gamma
      • Macrophage inflammatory protein 2 beta precursor
      • Macrophage inflammatory protein 2-beta
      • Melanoma growth stimulatory activity gamma
      • Member 3
      • MGSA gamma
      • MIP 2b
      • MIP2-beta
      • MIP2B
      • SCYB3
      • Small inducible cytokine subfamily B
      see all
    • Function

      Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications

      N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P19876 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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