Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CXCL1/GRO alpha protein (ab9806)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

Description

  • Product name

    Recombinant human CXCL1/GRO alpha protein
    See all CXCL1/GRO alpha proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      11 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9806 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized

      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • C-X-C motif chemokine 1
        • chemokine (C-X-C motif) ligand 1
        • Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
        • CINC-1
        • CXCL1
        • Cytokine-induced neutrophil chemoattractant 1
        • Fibroblast secretory protein
        • Fsp
        • Gro
        • Gro 1
        • Gro A
        • GRO protein, alpha
        • GRO-alpha(1-73)
        • GRO-alpha(6-73)
        • Gro1
        • Gro1 oncogene
        • GRO1 oncogene (melanoma growth stimulating activity, alpha)
        • GRO1 oncogene (melanoma growth-stimulating activity)
        • GROa
        • GROA_HUMAN
        • Growth-regulated alpha protein
        • KC
        • KC chemokine, mouse, homolog of
        • Melanoma growth stimulatory activity
        • melanoma growth stimulatory activity alpha
        • Melanoma growth stimulatory activity, alpha
        • MGSA
        • MGSA alpha
        • MGSA-a
        • N51
        • NAP-3
        • NAP3
        • Neutrophil-activating protein 3
        • Platelet-derived growth factor-inducible protein KC
        • Scyb 1
        • Scyb1
        • Secretory protein N51
        • Small inducible cytokine subfamily B, member 1
        see all

      • Function

        Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

      • Sequence similarities

        Belongs to the intercrine alpha (chemokine CxC) family.

      • Post-translational
        modifications

        N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab9806? Please let us know so that we can cite the reference in this datasheet.

    ab9806 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-X-C motif chemokine 1
      • chemokine (C-X-C motif) ligand 1
      • Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
      • CINC-1
      • CXCL1
      • Cytokine-induced neutrophil chemoattractant 1
      • Fibroblast secretory protein
      • Fsp
      • Gro
      • Gro 1
      • Gro A
      • GRO protein, alpha
      • GRO-alpha(1-73)
      • GRO-alpha(6-73)
      • Gro1
      • Gro1 oncogene
      • GRO1 oncogene (melanoma growth stimulating activity, alpha)
      • GRO1 oncogene (melanoma growth-stimulating activity)
      • GROa
      • GROA_HUMAN
      • Growth-regulated alpha protein
      • KC
      • KC chemokine, mouse, homolog of
      • Melanoma growth stimulatory activity
      • melanoma growth stimulatory activity alpha
      • Melanoma growth stimulatory activity, alpha
      • MGSA
      • MGSA alpha
      • MGSA-a
      • N51
      • NAP-3
      • NAP3
      • Neutrophil-activating protein 3
      • Platelet-derived growth factor-inducible protein KC
      • Scyb 1
      • Scyb1
      • Secretory protein N51
      • Small inducible cytokine subfamily B, member 1
      see all

    • Function

      Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.

    • Post-translational
      modifications

      N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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