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Signal Transduction Cytoskeleton / ECM Extracellular Matrix ECM Proteins

Recombinant Human Tenascin C protein (ab114943)

Recombinant Human Tenascin C protein (ab114943)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Wheat germ
  • Suitable for: ELISA, WB, SDS-PAGE

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Description

  • Product name

    Recombinant Human Tenascin C protein
  • Expression system

    Wheat germ
  • Accession

    P24821
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGK CVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN KPLCLNNCYN
    • Predicted molecular weight

      38 kDa including tags
    • Amino acids

      181 to 290

Preparation and Storage

  • Alternative names

    • 150 225
    • Cytotactin
    • Glioma associated extracellular matrix antigen
    • Glioma-associated-extracellular matrix antigen
    • GMEM
    • GP
    • GP 150 225
    • GP 150-225
    • Hexabrachion
    • HXB
    • JI
    • MGC167029
    • Miotendinous antigen
    • Myotendinous antigen
    • Neuronectin
    • TENA_HUMAN
    • Tenascin
    • Tenascin-C
    • Tenascin-C isoform 14/AD1/16
    • TenascinC
    • TN
    • TN C
    • TN-C
    • TNC
    see all
  • Function

    Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
  • Sequence similarities

    Belongs to the tenascin family.
    Contains 15 EGF-like domains.
    Contains 1 fibrinogen C-terminal domain.
    Contains 15 fibronectin type-III domains.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix.
  • Target information above from: UniProt accession P24821 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Tenascin C protein (ab114943)
    SDS-PAGE - Recombinant Human Tenascin C protein (ab114943)
    ab114943 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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