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Signal Transduction Signaling Pathway Nuclear Signaling STATs

Recombinant Human STAT6 protein (ab173040)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: HPLC, SDS-PAGE

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Description

  • Product name

    Recombinant Human STAT6 protein
    See all STAT6 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P42226
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMA PDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQM PPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQ PVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQ PSHYGQSGISMSLEHHHHHH
    • Predicted molecular weight

      24 kDa including tags
    • Amino acids

      627 to 837
    • Tags

      His tag C-Terminus
  • Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab173040 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Supplied as a 0.2 µM filtered solution.

    General Info

    • Alternative names

      • 12S1644
      • D12S1644
      • IL 4 STAT
      • IL-4 Stat
      • IL4 STAT
      • Interleukin 4 Induced
      • Interleukin 4 Induced Transcription Factor IL4 STAT
      • Signal transducer and activator of transcription 6
      • Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced
      • Signal Transducer And Activator Of Transcription 6 Nirs Variant 1
      • Signal transducer and activator of transcription 6, interleukin 4 induced
      • STAT 6
      • STAT interleukin4 induced
      • STAT, interleukin4 induced
      • Stat6
      • STAT6_HUMAN
      • STAT6B
      • STAT6C
      • Transcription factor IL 4 STAT
      see all
    • Function

      Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.
    • Sequence similarities

      Belongs to the transcription factor STAT family.
      Contains 1 SH2 domain.
    • Post-translational
      modifications

      Tyrosine phosphorylated following stimulation by IL-4 and IL-3.
    • Cellular localization

      Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
    • Target information above from: UniProt accession P42226 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab173040? Please let us know so that we can cite the reference in this datasheet.

    ab173040 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Supplied as a 0.2 µM filtered solution.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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